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<article xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="2.0">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JDERM</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Dermatol</journal-id>
      <journal-title>JMIR Dermatology</journal-title>
      <issn pub-type="epub">2562-0959</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v4i2e29723</article-id>
      <article-id pub-id-type="pmid">37632814</article-id>
      <article-id pub-id-type="doi">10.2196/29723</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Research Letter</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Research Letter</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Sunscreen Posts on Twitter in the United States and Canada, 2019: Content Analysis</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Dellavalle, MD, PhD, MSPH</surname>
            <given-names>Robert</given-names>
          </name>
        </contrib>
        <contrib contrib-type="editor">
          <name>
            <surname>Sivesind</surname>
            <given-names>Torunn</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Makin</surname>
            <given-names>Jen</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Fazel</surname>
            <given-names>Sajjad S</given-names>
          </name>
          <degrees>PharmD, MPH</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Department of Oncology</institution>
            <institution>Cumming School of Medicine</institution>
            <institution>University of Calgary</institution>
            <addr-line>3330 Hospital Dr NW</addr-line>
            <addr-line>Calgary, AB, T2N4N1</addr-line>
            <country>Canada</country>
            <email>sajjad.fazel@ucalgary.ca</email>
          </address>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-6457-4017</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Quinn</surname>
            <given-names>Emma K</given-names>
          </name>
          <degrees>BSc</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-3130-259X</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Ford-Sahibzada</surname>
            <given-names>Chelsea A</given-names>
          </name>
          <degrees>BSc</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-1788-9796</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Szarka</surname>
            <given-names>Steven</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-7736-0416</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>Peters</surname>
            <given-names>Cheryl E</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-1202-5689</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Department of Oncology</institution>
        <institution>Cumming School of Medicine</institution>
        <institution>University of Calgary</institution>
        <addr-line>Calgary, AB</addr-line>
        <country>Canada</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>CAREX Canada</institution>
        <institution>Simon Fraser University</institution>
        <addr-line>Vancouver, BC</addr-line>
        <country>Canada</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Cancer Epidemiology and Prevention Research</institution>
        <institution>Cancer Care Alberta</institution>
        <institution>Alberta Health Services</institution>
        <addr-line>Calgary, AB</addr-line>
        <country>Canada</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>School of Health Sciences</institution>
        <institution>University of Northern British Columbia</institution>
        <addr-line>Prince George, BC</addr-line>
        <country>Canada</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Sajjad S Fazel <email>sajjad.fazel@ucalgary.ca</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <season>Jul-Dec</season>
        <year>2021</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>19</day>
        <month>7</month>
        <year>2021</year>
      </pub-date>
      <volume>4</volume>
      <issue>2</issue>
      <elocation-id>e29723</elocation-id>
      <history>
        <date date-type="received">
          <day>18</day>
          <month>4</month>
          <year>2021</year>
        </date>
        <date date-type="rev-request">
          <day>3</day>
          <month>5</month>
          <year>2021</year>
        </date>
        <date date-type="rev-recd">
          <day>15</day>
          <month>6</month>
          <year>2021</year>
        </date>
        <date date-type="accepted">
          <day>16</day>
          <month>6</month>
          <year>2021</year>
        </date>
      </history>
      <copyright-statement>©Sajjad S Fazel, Emma K Quinn, Chelsea A Ford-Sahibzada, Steven Szarka, Cheryl E Peters. Originally published in JMIR Dermatology (http://derma.jmir.org), 19.07.2021.</copyright-statement>
      <copyright-year>2021</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Dermatology Research, is properly cited. The complete bibliographic information, a link to the original publication on http://derma.jmir.org, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://derma.jmir.org/2021/2/e29723" xlink:type="simple"/>
      <kwd-group>
        <kwd>sunscreen</kwd>
        <kwd>skin cancer</kwd>
        <kwd>Twitter</kwd>
        <kwd>misinformation</kwd>
        <kwd>prevention</kwd>
        <kwd>skin</kwd>
        <kwd>social media</kwd>
        <kwd>health promotion</kwd>
        <kwd>melanoma</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <p>Skin cancer is a growing burden in Canada and the United States. One effective prevention method is the use of sunscreen; however, low sunscreen use [<xref ref-type="bibr" rid="ref1">1</xref>] coupled with the spread of misinformation online can hinder health promotion activities.</p>
    <p>Health-related social media posts (including sunscreen) may shape risk-related behaviors of users, so it is important to understand the accuracy of such posts [<xref ref-type="bibr" rid="ref2">2</xref>].</p>
    <p>Twitter’s Application Program Interface was used to search for tweets in English containing the word “sunscreen” posted in Canada and the United States (May 1 to August 31, 2019). We used thematic content analysis to elicit the accuracy, sentiment, and theme of the tweets.</p>
    <p>Tweets containing verifiable information (that could be assessed as factual or not) were analyzed for accuracy and coded as either “accurate” or “inaccurate” based on current evidence. All tweets were coded for sentiment (positive or negative).</p>
    <p>Themes were analyzed using an a priori list of codes based on our previous study [<xref ref-type="bibr" rid="ref3">3</xref>] and inductively modified based on emergent themes. Differences were tested using the chi-square statistic or the Fisher exact test.</p>
    <p>In total, 9176 tweets were collected; 167 retweets and 85 irrelevant tweets were excluded. The remaining 8924 tweets were analyzed for accuracy (where applicable), sentiment, and theme. The observed percentage agreement between the coders for sentiment and accuracy was 76%. Only 395 tweets (4% of the total) contained verifiable information and were analyzed for accuracy. Among these, 277 (70%) were accurate and 118 (30%) were inaccurate (<xref rid="figure1" ref-type="fig">Figure 1</xref>).</p>
    <p>The most common themes were personal story (n=5425, 61%), tips and recommendations (n=2591, 28%), and advertisements (n=457, 5%). The top theme for accurate and inaccurate tweets was tips and recommendations (n=171, 56%) and personal story (n=90, 62%), respectively.</p>
    <fig id="figure1" position="float">
      <label>Figure 1</label>
      <caption>
        <p>Comparison of sentiments between accurate, inaccurate, and unverifiable sunscreen tweets originating from Canada and United States between May 1, 2019 and August 31, 2019.</p>
      </caption>
      <graphic xlink:href="derma_v4i2e29723_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
    </fig>
    <p>The sentiment analysis found that 7460 (84%) of tweets had a positive sentiment, 1031 (11%) were mixed or neutral, and 433 (5%) were negative. Among the accurate tweets, the majority had a positive sentiment toward sunscreen (n=248, 89%), while over half (n=64, 54%) of the inaccurate tweets had a negative sentiment. Interestingly, inaccurate tweets were more likely to have any engagement than accurate tweets (<xref ref-type="table" rid="table1">Table 1</xref>).</p>
    <p>We found that most tweets were personal stories and not verifiable for accuracy. This suggests that misinformation about sunscreen may not be an important contributor to low sunscreen use, as also noted by Silva et al [<xref ref-type="bibr" rid="ref4">4</xref>]. The sentiment analysis found that over 80% of all sunscreen tweets had a positive sentiment toward sunscreen use, which is similar to our previous study on sunscreen information in traditional media sources [<xref ref-type="bibr" rid="ref3">3</xref>].</p>
    <p>This study was limited to Twitter; further research on sunscreen misinformation using other social media platforms is recommended.</p>
    <p>In conclusion, sunscreen misinformation was limited, but misinformation was more likely to have engagement from users. Organizations may have better success in promoting sunscreen use by producing tailored, engaging sunscreen and cancer prevention messages [<xref ref-type="bibr" rid="ref5">5</xref>]. Furthermore, it may be beneficial for physicians and health organizations to share messages using lived experience, which may increase reach and engagement online.</p>
    <table-wrap position="float" id="table1">
      <label>Table 1</label>
      <caption>
        <p>Comparison of Twitter data between verifiable and unverifiable tweets: Canada and United States, 2019.</p>
      </caption>
      <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
        <col width="30"/>
        <col width="200"/>
        <col width="150"/>
        <col width="150"/>
        <col width="140"/>
        <col width="140"/>
        <col width="190"/>
        <thead>
          <tr valign="top">
            <td colspan="2">Category and subcategory</td>
            <td colspan="2">Verifiable tweets</td>
            <td><italic>P</italic> value (accurate vs inaccurate tweets)</td>
            <td>Unverifiable tweets, n (%)</td>
            <td><italic>P</italic> value (all verifiable vs unverifiable tweets)</td>
          </tr>
          <tr valign="top">
            <td colspan="2">
              <break/>
            </td>
            <td>Accurate tweets, n (%)</td>
            <td>Inaccurate tweets, n (%)</td>
            <td>
              <break/>
            </td>
            <td>
              <break/>
            </td>
            <td>
              <break/>
            </td>
          </tr>
        </thead>
        <tbody>
          <tr valign="top">
            <td colspan="2">
              <bold>Sentiment</bold>
            </td>
            <td colspan="2">
              <break/>
            </td>
            <td>&#60;.001</td>
            <td>
              <break/>
            </td>
            <td>&#60;.001</td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>Positive</td>
            <td>248 (89)</td>
            <td>29 (25)</td>
            <td>
              <break/>
            </td>
            <td>7183 (84)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>Mixed</td>
            <td>19 (7)</td>
            <td>25 (21)</td>
            <td>
              <break/>
            </td>
            <td>987 (12)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>Negative</td>
            <td>10 (4)</td>
            <td>64 (54)</td>
            <td>
              <break/>
            </td>
            <td>359 (4)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td colspan="2">
              <bold>Engagement<sup>a</sup></bold>
            </td>
            <td colspan="2">
              <break/>
            </td>
            <td>.04</td>
            <td>
              <break/>
            </td>
            <td>.68</td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>0</td>
            <td>96 (35)</td>
            <td>29 (25)</td>
            <td>
              <break/>
            </td>
            <td>2689 (32)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>1-5</td>
            <td>126 (46)</td>
            <td>66 (56)</td>
            <td>
              <break/>
            </td>
            <td>4269 (50)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>6-10</td>
            <td>18 (18)</td>
            <td>13 (11)</td>
            <td>
              <break/>
            </td>
            <td>711 (8)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>&#62;10</td>
            <td>37 (13)</td>
            <td>10 (8)</td>
            <td>
              <break/>
            </td>
            <td>860 (10)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td colspan="2">
              <bold>Followers<sup>b</sup></bold>
            </td>
            <td>
              <break/>
            </td>
            <td>
              <break/>
            </td>
            <td>.049</td>
            <td>
              <break/>
            </td>
            <td>.61</td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>0-200</td>
            <td>73 (26)</td>
            <td>28 (24)</td>
            <td>
              <break/>
            </td>
            <td>2011 (24)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>201-500</td>
            <td>55 (20)</td>
            <td>38 (32)</td>
            <td>
              <break/>
            </td>
            <td>2222 (26)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>501-1000</td>
            <td>58 (21)</td>
            <td>24 (20)</td>
            <td>
              <break/>
            </td>
            <td>1675 (20)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>&#62;1000</td>
            <td>91 (33)</td>
            <td>28 (24)</td>
            <td>
              <break/>
            </td>
            <td>2621 (31)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td colspan="2">
              <bold>Attached URL</bold>
            </td>
            <td colspan="2">
              <break/>
            </td>
            <td>&#60;.001</td>
            <td>
              <break/>
            </td>
            <td>&#60;.001</td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>Yes</td>
            <td>205 (74)</td>
            <td>60 (51)</td>
            <td>
              <break/>
            </td>
            <td>4349 (51)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>No</td>
            <td>72 (26)</td>
            <td>50 (49)</td>
            <td>
              <break/>
            </td>
            <td>4180 (49)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td colspan="2">
              <bold>Type of URL</bold>
            </td>
            <td colspan="2">
              <break/>
            </td>
            <td>.30</td>
            <td>
              <break/>
            </td>
            <td>&#60;.001</td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>Social media</td>
            <td>199 (88)</td>
            <td>50 (83)</td>
            <td>
              <break/>
            </td>
            <td>4214 (97)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>News</td>
            <td>5 (2)</td>
            <td>0 (0)</td>
            <td>
              <break/>
            </td>
            <td>88 (2)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>Health organizations</td>
            <td>4 (2)</td>
            <td>1 (2)</td>
            <td>
              <break/>
            </td>
            <td>18 (0.4)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>Peer-reviewed journal websites</td>
            <td>1 (0.5)</td>
            <td>1 (2)</td>
            <td>
              <break/>
            </td>
            <td>2 (0.05)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>Other</td>
            <td>17 (8)</td>
            <td>8 (13)</td>
            <td>
              <break/>
            </td>
            <td>268 (6)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td colspan="2">
              <bold>Attached media</bold>
            </td>
            <td colspan="2">
              <break/>
            </td>
            <td>.02</td>
            <td>
              <break/>
            </td>
            <td>.86</td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>Yes</td>
            <td>57 (21)</td>
            <td>13 (11)</td>
            <td>
              <break/>
            </td>
            <td>1482 (17)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>No</td>
            <td>220 (79)</td>
            <td>105 (89)</td>
            <td>
              <break/>
            </td>
            <td>7047 (83)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td colspan="2">
              <bold>Type of media</bold>
            </td>
            <td colspan="2">
              <break/>
            </td>
            <td>.87</td>
            <td>
              <break/>
            </td>
            <td>.26</td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>Photo</td>
            <td>46 (81)</td>
            <td>11 (85)</td>
            <td>
              <break/>
            </td>
            <td>1095 (74)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>Video</td>
            <td>1 (2)</td>
            <td>0 (0)</td>
            <td>
              <break/>
            </td>
            <td>82 (5)</td>
            <td>
              <break/>
            </td>
          </tr>
          <tr valign="top">
            <td>
              <break/>
            </td>
            <td>Animated GIF</td>
            <td>10 (17)</td>
            <td>2 (15)</td>
            <td>
              <break/>
            </td>
            <td>305 (21)</td>
            <td>
              <break/>
            </td>
          </tr>
        </tbody>
      </table>
      <table-wrap-foot>
        <fn id="table1fn1">
          <p><sup>a</sup>Engagement was defined as the total number of “likes,” “retweets,” “quote tweets,” and “replies” for each tweet.</p>
        </fn>
        <fn id="table1fn2">
          <p><sup>b</sup>Followers was defined as the number of individual Twitter accounts following the user.</p>
        </fn>
      </table-wrap-foot>
    </table-wrap>
  </body>
  <back>
    <app-group/>
    <ack>
      <p>This research received no external funding.</p>
    </ack>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Pinault</surname>
              <given-names>L</given-names>
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