This multicenter, cross-sectional study was conducted at 1 secondary and 2 tertiary referral centers for dermatology in Switzerland. We applied a customized questionnaire from August 1, 2019, to January 31, 2020, at the Department of Dermatology of the University Hospitals of Basel and Zurich and at the Cantonal Hospital of Aarau. The questionnaire was offered to all patients aged 18 years and older at check-in and anonymously completed in the waiting room before the appointment with the dermatologist at the mentioned centers. We also sent an adapted version of the questionnaire to all dermatologists and medical staff (nurses and secretaries) at these hospitals (henceforth referred to as “health care workers”) to be completed at any time. The questionnaire was also applied to other physicians who do not work in dermatology; however, these data were not included in this study. Overall, 70.6% (512/725) of the patients, 72.6% (45/62) of the dermatologists, and 68.6% (107/156) of the health care workers responded to the questionnaire. Exclusion criteria were language barriers, cognitive impairment, and a lack of informed consent.

We designed the questionnaire in German to assess individual characteristics and telemedicine-related aspects in patients (see questionnaire Q-A in Multimedia Appendix 1), as well as in physicians and health care workers (see questionnaire Q-B in Multimedia Appendix 2). A total of 12 questionnaire items were identical across cohorts. The questionnaire addressed demographics, educational, and economic data (currency was converted from Swiss Francs to Euros [1.0 CHF=1.0 Euro, July 4, 2022]), as well as aspects of individual experience with and opinion about telemedicine. Here, we only assessed the presumed willingness to replace in-person consultation and the overall experience with telemedicine, as well as their associations with individual characteristics. The 4 different categories of acuity and severity (minor, severe, acute, and chronic) were defined as the subjective, individual judgment of each participant for the acuity and severity of skin diseases. Other aspects of the questionnaire will be published later. Depending on the question, possible answers were either binary (yes/no), multiple choice, visual analog scales (VASs) with scores from 0-10, or free text.

We reported the proportions of primary answers and investigated the differences in the questionnaire answers related to the previous use of telemedicine (Q-A #12a, Q-B #5), additional in-person consultation to the telemedicine (Q-A #15, Q-B #8), media for telemedicine (Q-A #14, Q-B #7), overall experience with telemedicine consultation (Q-A #16, Q-B #9), presumed willingness to replace in-person consultation with telemedicine (Q-A #19, Q-B #11), preference for telemedicine or in-person consultation (Q-A #17-18, Q-B #10), and individual differences (Q-A #0-2, Q-B #0-2) across the 3 different cohorts (here defined as patients, physicians, and health care workers). Differences in proportion of answers across cohorts were explored with chi-square tests, with Monte-Carlo resampling with 10,000 iterations if the frequency in any cell was less than 5. Differences in answers for presumed willingness to replace in-person consultation with telemedicine across cohorts were evaluated for different severities (minor and severe) and acuities (chronic and acute) of skin problems. Differences in answers for preference for telemedicine or in-person consultation across individual differences were evaluated for each cohort separately. Differences in age were explored with the Kruskal-Wallis test. P values were adjusted for multiple comparisons using the false discovery rate (FDR) for each analysis separately. All analyses were performed through R (versions 3.6.2 and 4.2.0; The R Foundation) and Python version 3.7.6 (Python Software Foundation).

The study was approved by the Northwest and Central Switzerland Ethics Committee (2019-00523) and was registered with ClinicalTrials.gov (NCT04495036). The study was conducted in full compliance with the Declaration of Helsinki (1964) and Good Clinical Practice was maintained throughout the study.

A total of 512 dermatological patients (mean age 49.5, SD 17.9 years; 239/512, 46.7% women), 45 dermatologists (mean age 34.1 SD 8.5 years; 32/45, 71.1% women) and 107 health care workers (mean age 38.6, SD 13.0 years; 88/107, 82.2% women) completed the questionnaire (a total of 664 individuals). Information about nationality, place of residence, monthly salary, highest level of education, work experience, and previous use of telemedical services for patients, physicians, and health care workers is summarized in Table 1.

Considering only individuals who reported having already used telemedicine (henceforth referred to as “telemedicine users”; Q-A #12a, Q-B #5, Table 1) and having an in-person consultation for the same medical problem (Q-A #15, Q-B #8), telemedicine was used before rather than after an in-person consultation by 84.4% (54/64) of the patients, 83.3% (5/6) of the dermatologists, 92.3% (24/26) of the health care workers and we observed no differences across cohorts (χ²=1.1; P=.70).

Considering only previous telemedicine users (Q-A #12a, Q-B #5, Table 1), the overall experience with telemedicine from patients’ perspective within all 3 target group was rated as either “very good” or “good” by 68.9% (73/106) of the patients, 75.0% (6/8) of the physicians, and by 79.4% (27/34) of the health care workers (Q-A #16, Q-B #9, Table 2) and we observed no differences across cohorts (χ²=7.3; P=.50, Table 2), excluding the “not applicable/did not answer” responses. We also report information about media used for telemedicine counselling in Table S1 in Multimedia Appendix 3 (Q-A #14, Q-B #7).

Considering all respondents, they reported that they could consider replacing the in-person consultation with telemedicine for minor skin problems (patients: 353/512, 68.9%; dermatologists: 37/45, 82.2%; and health care workers: 89/107, 83.2%), but not for severe (patients: 30/512, 5.9%; dermatologists: 4/45, 8.9%; and health care workers: 7/107, 6.5%), acute (patients: 122/512, 23.8%; dermatologists: 22/45, 48.9%; and health care workers: 39/107, 36.4%), and chronic skin problems (patients: 120/512, 23.4%; dermatologists: 19/45, 42.2%; and health care workers: 37/107, 34.6%; Q-A #19, Q-B #11, Table 3).

We observed differences across cohorts in the responses when individuals were asked if they could consider replacing in-person consultation with telemedicine for minor (χ²₂=7.09; P=.04), acute (χ²₂=12.95; P=.008), and chronic (χ²₂=8.12; P=.03) skin problems, but not for severe skin problems. Nonresponses (not applicable or did not answer) have not been included in statistical tests (Q-A #19, Q-B #11, Table 3, Figure 1). Post hoc analyses revealed a lower presumed willingness to replace in-person consultation with telemedicine for minor and chronic skin problems among patients compared to other cohorts. Furthermore, post hoc analyses also revealed a higher presumed willingness to replace in-person consultation with telemedicine for acute skin problems among physicians compared to other cohorts.

Considering all respondents (ie, including individuals with no previous experience with telemedicine), the reported preference as a patient for telemedicine or in-person consultation (Q-A #17, Q-B #10) across skin problems and several individual characteristics for all cohorts is shown in Table S2 in Multimedia Appendix 3.

Analyzing the cohorts separately, we observed differences in preference for telemedicine or in-person consultation (or no preference) with patient age (Q-A #0.1; P=.01) and physician age (Q-B #0.1; P=.02) (Table S2 in Multimedia Appendix 3, Figure 2). Post hoc analysis showed that the age of those who reported preferring in-person consultation was higher than the age of those who reported no preference, with no difference between in-person consultation and telemedicine. In addition, we observed that patients’ preferences for telemedicine or in-person consultation were different across education levels (χ²=24.6; P<.001; Q-A #0.5, Figure 3). Post hoc analysis indicated a higher preference for telemedicine in patients with university degrees compared to other levels of education.

Furthermore, we observed that the preference of patients (χ²₂=15.6; P<.001), dermatologists (χ²₂=7.87; P=.03), and health care workers (χ²=10.3; P=.005) for telemedicine depended on their previous telemedicine experience (Q-A #12a, Q-B #5, Figure 4). Post hoc analyses indicated that, with previous telemedicine experience, there is a higher preference for telemedicine and lower preference for in-person consultation among patients; a higher preference for in-person consultation among physicians; and a higher reporting of no preference and lower preference for in-person consultation among health care workers. We observed no other differences in preference for telemedicine for the other considered individual characteristics, for either the cohorts analyzed separately (Table S2 in Multimedia Appendix 3) or for patients currently using telemedicine (Table S3 in Multimedia Appendix 3).

Understanding the population’s current attitudes toward telemedicine is highly relevant to optimizing the transition to teledermatology. We found that individuals who have previously used telemedicine reported a high level of overall experience with it. Patients, health care workers, and physicians reported that they would consider replacing in-person consultations with telemedicine for minor health issues. We observed a higher preference for telemedicine among patients with higher levels of education and among individuals who had previous experience with telemedicine.

This study revealed high overall experience among all individuals with their use of telemedicine (between 68.9% and 79.4%), which is consistent with previous studies [35-37]. However, satisfaction with telemedicine is controversial. In a comparative study with 121 patients, only 44% of them reported satisfaction with telemedicine, while 10% of them reported dissatisfaction [38]. Despite the relevance of better understanding the perspectives of medical staff and nonmedical staff, this study is the first to examine the physicians and health care workers’ level of overall experience with telemedicine from their perspective as patients, to the best of our knowledge.

The COVID-19 pandemic has triggered a new era in telemedicine with an immense increase in applications within various medical fields [39,40], as telemedicine has minimized the hazard of direct exposure to individuals during the pandemic. A Brazilian study identified that the posture toward telemedicine of physicians as providers was positively influenced and significantly increased from 18.5% before the pandemic to 63.6% during the COVID-19 period [41]. Furthermore, over 70% of patients at New York University Langone Health reported being satisfied with live-interactive teledermatology during the pandemic in 2020 [42]. Our findings indicate that the overall experience with telemedicine in the Swiss-German population was already comparably high before the pandemic. We further postulate that our findings on the level of overall experience should now be even higher than reported here, as pandemic conditions have further strengthened telemedicine services.

In the context of teledermatology, we found that the presumed willingness to replace in-person consultation with telemedicine depends on the severity and acuity of the skin problem. Most patients, physicians, and health care workers favored replacement for minor skin problems. We observed that, among the cohorts analyzed, the highest level of acceptance for telemedicine for acute and chronic skin problems was among physicians. Most participants would not consider replacing in-person consultations with telemedicine for severe skin issues.

Previous studies have suggested that in-person consultations cannot generally be replaced by telemedicine [43,44]. The identification of the most suitable indications for telehealth versus traditional consultations is crucial for maintaining patients’ safety and satisfaction. The COVID-19 pandemic has transformed the health care system through a sudden expansion of telemedicine for nonurgent and urgent care [40]. Data from the pandemic period showed an increase of 683% in teledermatology usage in the United States, particularly for urgent care [45]. Even during the pandemic, the patients preferred in-person consultations over telemedicine for severe conditions [45], which is consistent with our pre–COVID-19 findings.

On the other hand, a systematic review indicated that, for particular situations, telemedicine can adequately replace in-person consultation [46]. The willingness to use telemedicine after the pandemic was reported by many studies [46]. One study reported that only a minority of patients (36%) consider that telemedicine is not appropriate to replace in-person consultations [47]. We suggest that teledermatology services should take into account the acuity and severity of skin problems in the future and thereby focus on the diagnoses best handled with telemedicine.

Our data indicate that patients, physicians, and health care workers with experience in telemedicine and patients with a higher educational level showed a higher preference for telemedicine. As expected, older patients and physicians favored in-person consultations.

Our findings imply that one of the main problems telemedicine is facing is trust among new patients. We observed that a first experience with telemedicine influences one’s attitude toward it positively. As we detected that there is somehow a barrier to the first use of telemedicine, some acclimatization needs to occur [48]. In a previous study with 184 teledermatology patients, telemedicine experience was also associated with a higher odds ratio of preferring teledermatology in the future [49]. Also, during the COVID-19 pandemic, first-time teledermatology patients in the United States reported being less satisfied with telemedicine communication [36].

Furthermore, we also observed that a high preference for telemedicine was associated with a higher educational level. We suggest that the finding is related to the increased attitude of highly educated individuals to inform themselves about new technologies and to have sufficient technical skills [50].

This study indicates that older patients and physicians prefer in-person consultations over telemedicine. An American study with >600 participants reported that patients older than 66 years of age preferred in-person consultation and follow-up during the COVID-19 pandemic [42]. In fact, another study indicated higher satisfaction rates with telemedicine among patients younger than 56 years of age and without suspected cancer [51]. While studies focusing only on teledermatology generally report higher levels of satisfaction, direct comparative studies of in-person consultations and telemedicine report mixed outcomes [26,51-56]. Consistent with our findings, a questionnaire-based survey among 720 patients in Saudi Arabia during the COVID-19 pandemic showed that older age (over 40 years), lower education levels, and first-time experience were associated with poor-to-average satisfaction with telemedicine [57].

We identified factors associated with a lower preference for teledermatology: older age, lower education, and no experience with telemedicine. As teledermatology becomes more prominent, these cohorts may develop disparities in care. Therefore, we propose that the following steps should be considered to increase acceptance of teledermatology: minimization of technical barriers by simple handling of the telemedical offers as well as increasing the attractiveness of the first telemedicine consultation through reduced waiting time and cost savings.

Despite technological improvements, such as increased access to mobile phones and high-resolution screening, the latest studies about satisfaction with teledermatology revealed that patients and dermatologists still prefer in-person examinations [51,58]. We speculate that this reluctance to use telemedicine may be related to accessibility skills and previous knowledge about telemedicine. Future assessments could be designed to guide us in handling teledermatology as a screening tool.

The era of telemedicine has also opened new horizons for rapid digital professional exchange of expertise between physicians of different specialties and the ability to obtain a second opinion [13,59,60]. Tele-expertise is cost-effective as patients can reduce doctor -patient contact with a specialist [61]. Remote areas and the pandemic have taught us that tele-expertise alongside teledermatology is of high importance because access to primary care is limited, especially in these scenarios [62]. Future studies focusing on the challenges, integration, and quality of tele-expertise in relation to telemedicine are needed.

This study has some limitations. First, there was a low number of dermatologists and health care workers since we predefined the centers. This is also the reason why sample size was not beforehand determined, but we aimed to maximize the sampling given our time and site predefinitions. While this study might be minimally representative of the dermatologists’ perspective in German-speaking Switzerland working at massive health care centers, it may be difficult to generalize the findings to a larger population of medical professionals. We suggest that data for dermatologists should be viewed with caution when interpreting the emerging patterns. Second, our findings may not be generalizable outside of Switzerland. However, as our results were consistent with related literature, we speculate that it is likely that our findings can be reproduced in similar cultures. Third, the results might have been influenced by confounders, such as dermatologists being mostly women and living in large cities. Thus, we cannot really conclude if the differences are due to their gender, profession, and place of residence. Further research assessing the acceptance of teledermatology in a larger study population, especially also in countries with a geographically challenging health care situation and including the distinction between live-interactive and store-and-forward applications will help to better understand the impending value of telemedicine. Due to a lack of usage of nonvalidated scales to measure the variables, our results’ value might be less important in scientific research but has a higher impact on clinical daily routines and health policy makers.

This study indicates that acceptance and preference for teledermatology have a high potential to increase over time as they depend on experience with telemedicine. Acclimatization is needed for new users and providers. We assume that minor skin problems are the most promising field for teledermatology, and thus we suggest focusing on them for further development. This study indicated that within the 3 target groups, 65.4% to 80% of individuals were overchallenged with the question of whether their insurance covers telemedicine services. This finding provides a relevant insight for health policy makers and health insurance managers. The reimbursement of telemedicine services is not yet regulated evenly within countries and globally which reflects the ongoing debate of its acceptance. There is a high need to expand telemedicine and teledermatology in order to provide access to medicine and care for patients globally. We provide new insights into the telemedicine situation in German-speaking Switzerland and emphasize the need for dermatologists to be actively involved in the transition to teledermatology. Future studies integrating well-established models such as UTAUT2 are required to focus on an in-depth view of the different target groups after the outbreak of the pandemic.