<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="review-article"><front><journal-meta><journal-id journal-id-type="nlm-ta">JMIR Dermatol</journal-id><journal-id journal-id-type="publisher-id">derma</journal-id><journal-id journal-id-type="index">29</journal-id><journal-title>JMIR Dermatology</journal-title><abbrev-journal-title>JMIR Dermatol</abbrev-journal-title><issn pub-type="epub">2562-0959</issn><publisher><publisher-name>JMIR Publications</publisher-name><publisher-loc>Toronto, Canada</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">v9i1e78385</article-id><article-id pub-id-type="doi">10.2196/78385</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Navigating the Intersection of Radiofrequency Microneedling and Surgical Facelifts: Scoping Review</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name name-style="western"><surname>Panlilio</surname><given-names>Mia</given-names></name><degrees>BA</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Bolen</surname><given-names>Rebecca</given-names></name><degrees>BA</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Martini</surname><given-names>Olnita</given-names></name><degrees>MS</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Bonk</surname><given-names>Alexa</given-names></name><degrees>BS</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Tedesco</surname><given-names>John</given-names></name><degrees>DO</degrees><xref ref-type="aff" rid="aff2">2</xref></contrib></contrib-group><aff id="aff1"><institution>Department of Biomedical Sciences, College of Osteopathic Medicine, Rocky Vista University</institution><addr-line>8401 S Chambers Rd</addr-line><addr-line>Englewood</addr-line><addr-line>CO</addr-line><country>United States</country></aff><aff id="aff2"><institution>College of Osteopathic Medicine, Oklahoma State University</institution><addr-line>Tulsa</addr-line><addr-line>OK</addr-line><country>United States</country></aff><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Dellavalle</surname><given-names>Robert</given-names></name></contrib></contrib-group><contrib-group><contrib contrib-type="reviewer"><name name-style="western"><surname>Edalatpour</surname><given-names>Armin</given-names></name></contrib><contrib contrib-type="reviewer"><name name-style="western"><surname>Huang</surname><given-names>Patrick</given-names></name></contrib></contrib-group><author-notes><corresp>Correspondence to Mia Panlilio, BA, Department of Biomedical Sciences, College of Osteopathic Medicine, Rocky Vista University, 8401 S Chambers Rd, Englewood, CO, 80112, United States, 1 9253236431; <email>mia.panlilio@ut.rvu.edu</email></corresp></author-notes><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>27</day><month>4</month><year>2026</year></pub-date><volume>9</volume><elocation-id>e78385</elocation-id><history><date date-type="received"><day>01</day><month>06</month><year>2025</year></date><date date-type="rev-recd"><day>08</day><month>12</month><year>2025</year></date><date date-type="accepted"><day>06</day><month>01</month><year>2026</year></date></history><copyright-statement>&#x00A9; Mia Panlilio, Rebecca Bolen, Olnita Martini, Alexa Bonk, John Tedesco. Originally published in JMIR Dermatology (<ext-link ext-link-type="uri" xlink:href="http://derma.jmir.org">http://derma.jmir.org</ext-link>), 27.4.2026. </copyright-statement><copyright-year>2026</copyright-year><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Dermatology, is properly cited. The complete bibliographic information, a link to the original publication on <ext-link ext-link-type="uri" xlink:href="http://derma.jmir.org">http://derma.jmir.org</ext-link>, as well as this copyright and license information must be included.</p></license><self-uri xlink:type="simple" xlink:href="https://derma.jmir.org/2026/1/e78385"/><abstract><sec><title>Background</title><p>Optimal management of facial skin laxity requires a nuanced approach by health care providers working in aesthetics. Radiofrequency microneedling (RFMN) devices have emerged as a popular noninvasive treatment for facial rejuvenation and improving skin laxity. While RFMN has demonstrated efficacy in enhancing skin tightening and complementing aesthetic procedures, its long-term impact on subsequent surgical facelifts remains uncertain.</p></sec><sec><title>Objective</title><p>The objective of this scoping review is to explore the interplay between RFMN and surgical facelift outcomes, with a focus on potential complications such as excessive skin tightening, dermal scarring, and altered tissue planes that may pose surgical challenges.</p></sec><sec sec-type="methods"><title>Methods</title><p>A search using PubMed and Google Scholar was conducted, and articles were selected from peer-reviewed journals based on specific inclusion and exclusion criteria. Only articles available in English were selected. In total, 21 articles were included in this scoping review.</p></sec><sec sec-type="results"><title>Results</title><p>Papers included in this review discussed the mechanisms of action involved with RFMN, RFMN-related tissue changes, and how these changes could impact future facelift procedures. Most of the papers found that RFMN may drastically alter multiple tissue planes involved in facelift procedures due to collagen deposition through multiple tissue layers and increased tissue fibrosis. Patient factors influencing the effectiveness of RFMN and its role in facial rejuvenation were also examined, emphasizing the importance of navigating patient-specific demographics as a future consideration when creating an individualized treatment plan for each patient.</p></sec><sec sec-type="conclusions"><title>Conclusions</title><p>Patients should be informed that RFMN may lead to dermal fibrosis, tissue adhesions, and altered superficial musculoaponeurotic system composition, which could interfere with future facelift procedures and the patient&#x2019;s desired treatment goals. This emphasizes the importance of detailed discussion between the patient and health care provider to improve pretreatment consultation, increase patient education, and set realistic expectations. Further research is needed to determine optimal timing and treatment strategies for patients considering both RFMN and surgical facelifts to achieve the best aesthetic outcomes.</p></sec></abstract><kwd-group><kwd>radiofrequency</kwd><kwd>microneedling</kwd><kwd>facial</kwd><kwd>laxity</kwd><kwd>facelift</kwd></kwd-group></article-meta></front><body><sec id="s1" sec-type="intro"><title>Introduction</title><p>Radiofrequency (RFMN) microneedling is a minimally invasive procedure that combines mechanical injury and thermal stimulation via tiny microneedles with radiofrequency (RF) energy to induce collagen remodeling [<xref ref-type="bibr" rid="ref1">1</xref>]. The microneedling component creates controlled microtraumas, triggering a postinflammatory cascade that promotes neocollagenesis, elastin production, and angiogenesis. RF energy delivered through the microneedles then generates thermal coagulation within the dermis and hypodermis to induce collagen denaturation and subsequent contraction of tissue for skin tightening benefits [<xref ref-type="bibr" rid="ref2">2</xref>]. This fractional approach allows for targeted treatment while preserving surrounding tissue, reducing recovery time [<xref ref-type="bibr" rid="ref3">3</xref>]. Compared to traditional microneedling, evidence suggests that RFMN brings about greater improvements in aged skin, likely by eliminating senescent fibroblasts and increasing the number of nonsenescent fibroblasts [<xref ref-type="bibr" rid="ref4">4</xref>].</p><p>A systematic review done in 2021 by Tan et al [<xref ref-type="bibr" rid="ref5">5</xref>] analyzed 42 studies evaluating RFMN use across various conditions, with the largest evidence base for skin rejuvenation, followed by acne scars, acne vulgaris, striae, and axillary hyperhidrosis. A smaller number of studies were available supporting RFMN use for melasma, rosacea, cellulite, and androgenetic alopecia.</p><p>Based on the large and growing body of evidence for skin rejuvenation, RFMN devices have gained immense popularity for addressing skin laxity in patients seeking noninvasive alternatives to surgical facelifts. These devices offer treatment options for individuals outside the average age range for a facelift, those who have previously undergone a facelift, or patients desiring minimally invasive interventions [<xref ref-type="bibr" rid="ref5">5</xref>]. Advances in RFMN technology, such as interchangeable tips with various microneedle pin configurations and dual treatment modes, allow for targeted treatments in delicate anatomical areas like the periorbital region [<xref ref-type="bibr" rid="ref5">5</xref>]. While these technological refinements enhance customization, the process may impact deeper dermal structures critical to surgical outcomes, setting the stage for potential interference with future facelift procedures.</p><p>Long-term effects of RFMN before surgical facelifts remain unclear, raising concerns about potential complications. RFMN treatment prior to an elective facelift may have the potential to interfere with optimal facelift results due to excessive skin tightening, scarring, and damage to the dermis. This emphasizes the importance of pretreatment discussion about expectations and the adverse effects of RFMN if it is being used with a patient who is considering a facelift in the future. Given the interplay between RFMN and surgical facelifts, what are the long-term implications of RFMN for patients who may eventually pursue surgical facelift procedures? Could the very technology we&#x2019;re using to delay surgery unintentionally complicate it later? This scoping review explores the anatomical and clinical intersections between RFMN and surgical facelifts for patients realistically considering either a facelift or RFMN. It draws on current literature, evolving device technology, and real-world considerations to guide thoughtful treatment planning for optimal patient outcomes.</p></sec><sec id="s2" sec-type="methods"><title>Methods</title><p>Searches done on PubMed and Google Scholar using the terms &#x201C;skin laxity and radiofrequency microneedling,&#x201D; &#x201C;skin laxity and microneedling,&#x201D; &#x201C;skin laxity and facelift,&#x201D; &#x201C;facelift and radiofrequency microneedling,&#x201D; and &#x201C;facelift and microneedling&#x201D; were conducted on January 4, 2024, and again on June 20, 2025, to account for any newly published or updated literature since the original search. The second search did not yield any new articles. Articles from peer-reviewed journals were included if they provided information on the mechanism of action of RFMN, described the techniques involved when performing a facelift procedure, or examined the effects of RFMN and/or facelift procedures on the skin. Only articles available in English were selected, and articles were excluded if they provided information on the use of RFMN on parts of the body other than the face and neck, or if they described RFMN treatment or surgical intervention unrelated to improving facial skin laxity. A summary of the inclusion and exclusion criteria are highlighted in <xref ref-type="other" rid="box1">Textbox 1</xref>. The review was conducted based on the 2005 methodology of Arksey and O&#x2019;Malley [<xref ref-type="bibr" rid="ref6">6</xref>]. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) reporting guidelines were followed, and the completed PRISMA-ScR checklist for this review can be found as <xref ref-type="supplementary-material" rid="app1">Checklist 1</xref>.</p><boxed-text id="box1"><title> Inclusion and exclusion criteria.</title><p><bold>Inclusion criteria</bold></p><list list-type="bullet"><list-item><p>From peer-reviewed journals</p></list-item><list-item><p>Content of article: mechanism of action of radiofrequency microneedling (RFMN); facelift procedures; effects of RFMN and/or facelift procedures on the skin</p></list-item><list-item><p>Available in English</p></list-item></list><p><bold>Exclusion criteria</bold></p><list list-type="bullet"><list-item><p>Content of article: RFMN being used on parts of the body other than the face and neck; RFMN treatment or surgical intervention unrelated to improving facial skin laxity</p></list-item><list-item><p>Not available in English or an English translation</p></list-item></list></boxed-text></sec><sec id="s3" sec-type="results"><title>Results</title><sec id="s3-1"><title>Article Selection</title><p>From the initial search using the selected search terms, 15,934 and 293 articles were respectively identified from Google Scholar and PubMed, for a total of 16,277 articles (<xref ref-type="fig" rid="figure1">Figure 1</xref>). Out of the 16,277 articles screened, 16 PubMed articles were excluded because they were not available in English. Google Scholar does not have a language screening filter, so all 15,934 articles from the initial search were still considered. After all authors screened the remaining articles for content based on the inclusion and exclusion criteria, 21 articles in total were selected for this review. A PRISMA diagram of the article selection is available below in <xref ref-type="fig" rid="figure1">Figure 1</xref>.</p><fig position="float" id="figure1"><label>Figure 1.</label><caption><p>Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) diagram of article selection.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="derma_v9i1e78385_fig01.png"/></fig></sec><sec id="s3-2"><title>Summary of Included Articles</title><p>After article screening was completed and the 21 articles were selected, 12 articles were identified as original research, 5 as narrative literature reviews, 2 as systematic reviews, and 1 as an educational reference article. One article, by Arksey and O&#x2019;Malley [<xref ref-type="bibr" rid="ref6">6</xref>], was used as a framework to guide writing of this review, and did not necessarily fit the inclusion and exclusion criteria for articles specifically related to the topic of this scoping review. <xref ref-type="table" rid="table1">Table 1</xref> displays a summary of the articles mentioned, as well as their article types and study designs.</p><table-wrap id="t1" position="float"><label>Table 1.</label><caption><p>Summary of included articles.</p></caption><table id="table1" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Authors (year)</td><td align="left" valign="bottom">Journal</td><td align="left" valign="bottom">Article type</td><td align="left" valign="bottom">Study design</td></tr></thead><tbody><tr><td align="left" valign="top">Devgan et al (2019) [<xref ref-type="bibr" rid="ref1">1</xref>]</td><td align="left" valign="top"><italic>Otolaryngology Clinics of North America</italic></td><td align="left" valign="top">Literature review</td><td align="left" valign="top">Narrative review</td></tr><tr><td align="left" valign="top">Spataro et al (2022) [<xref ref-type="bibr" rid="ref2">2</xref>]</td><td align="left" valign="top"><italic>Facial Plastic Surgery Clinics of North America</italic></td><td align="left" valign="top">Literature review</td><td align="left" valign="top">Narrative review</td></tr><tr><td align="left" valign="top">Hendricks and Farhang (2022) [<xref ref-type="bibr" rid="ref3">3</xref>]</td><td align="left" valign="top"><italic>Journal of Cosmetic Dermatology</italic></td><td align="left" valign="top">Literature review</td><td align="left" valign="top">Narrative review</td></tr><tr><td align="left" valign="top">Hwang et al (2025) [<xref ref-type="bibr" rid="ref4">4</xref>]</td><td align="left" valign="top"><italic>Scientific Reports</italic></td><td align="left" valign="top">Original research</td><td align="left" valign="top">Split-face comparative clinical trial</td></tr><tr><td align="left" valign="top">Tan et al (2021) [<xref ref-type="bibr" rid="ref5">5</xref>]</td><td align="left" valign="top"><italic>Dermatologic Surgery</italic></td><td align="left" valign="top">Literature review</td><td align="left" valign="top">Narrative review</td></tr><tr><td align="left" valign="top">Arksey and O&#x2019;Malley (2005) [<xref ref-type="bibr" rid="ref6">6</xref>]</td><td align="left" valign="top"><italic>International Journal of Social Research Methodology</italic></td><td align="left" valign="top">Original research</td><td align="left" valign="top">Not applicable</td></tr><tr><td align="left" valign="top">Dayan et al (2020) [<xref ref-type="bibr" rid="ref7">7</xref>]</td><td align="left" valign="top"><italic>Plastic and Reconstructive Surgery&#x2014;Global Open</italic></td><td align="left" valign="top">Original research</td><td align="left" valign="top">Prospective case series (single-arm clinical study)</td></tr><tr><td align="left" valign="top">Arnaoutakis et al (2022) [<xref ref-type="bibr" rid="ref8">8</xref>]</td><td align="left" valign="top"><italic>Facial Plastic Surgery &#x0026; Aesthetic Medicine</italic></td><td align="left" valign="top">Literature review</td><td align="left" valign="top">Narrative review</td></tr><tr><td align="left" valign="top">Ramaut et al (2018) [<xref ref-type="bibr" rid="ref9">9</xref>]</td><td align="left" valign="top"><italic>Journal of Plastic, Reconstructive &#x0026; Aesthetic Surgery</italic></td><td align="left" valign="top">Systematic review</td><td align="left" valign="top">Systematic review</td></tr><tr><td align="left" valign="top">Huang et al (2014) [<xref ref-type="bibr" rid="ref10">10</xref>]</td><td align="left" valign="top"><italic>Biochemistry</italic></td><td align="left" valign="top">Basic science research</td><td align="left" valign="top">In vitro experimental study</td></tr><tr><td align="left" valign="top">Nguyen et al (2025) [<xref ref-type="bibr" rid="ref11">11</xref>]</td><td align="left" valign="top"><italic>Lasers in Medical Science</italic></td><td align="left" valign="top">Original article</td><td align="left" valign="top">Clinical and histologic study (prospective cohort)</td></tr><tr><td align="left" valign="top">Xu et al (2025) [<xref ref-type="bibr" rid="ref12">12</xref>]</td><td align="left" valign="top"><italic>Lasers in Surgery and Medicine</italic></td><td align="left" valign="top">Original research</td><td align="left" valign="top">Animal study (porcine model)</td></tr><tr><td align="left" valign="top">Zheng et al (2014) [<xref ref-type="bibr" rid="ref13">13</xref>]</td><td align="left" valign="top"><italic>Dermatologic Surgery</italic></td><td align="left" valign="top">Original research</td><td align="left" valign="top">Experimental histologic study</td></tr><tr><td align="left" valign="top">Wang et al (2025) [<xref ref-type="bibr" rid="ref14">14</xref>]</td><td align="left" valign="top"><italic>Lasers in Medical Science</italic></td><td align="left" valign="top">Original research</td><td align="left" valign="top">Pilot clinical study</td></tr><tr><td align="left" valign="top">Wang et al (2024) [<xref ref-type="bibr" rid="ref15">15</xref>]</td><td align="left" valign="top"><italic>Lasers in Surgery and Medicine</italic></td><td align="left" valign="top">Original research</td><td align="left" valign="top">Animal study (porcine model)</td></tr><tr><td align="left" valign="top">Cho et al (2024) [<xref ref-type="bibr" rid="ref16">16</xref>]</td><td align="left" valign="top"><italic>Skin Research &#x0026; Technology</italic></td><td align="left" valign="top">Original research</td><td align="left" valign="top">Animal study (minipig model)</td></tr><tr><td align="left" valign="top">Hohman et al (2023) [<xref ref-type="bibr" rid="ref17">17</xref>]</td><td align="left" valign="top"><italic>StatPearls</italic></td><td align="left" valign="top">Reference article</td><td align="left" valign="top">Narrative review (educational)</td></tr><tr><td align="left" valign="top">Ghassemi et al (2003) [<xref ref-type="bibr" rid="ref18">18</xref>]</td><td align="left" valign="top"><italic>Aesthetic Plastic Surgery</italic></td><td align="left" valign="top">Original research</td><td align="left" valign="top">Anatomical cadaveric study</td></tr><tr><td align="left" valign="top">Demesh et al (2021) [<xref ref-type="bibr" rid="ref19">19</xref>]</td><td align="left" valign="top"><italic>Journal of Cosmetic Dermatology</italic></td><td align="left" valign="top">Original research</td><td align="left" valign="top">Clinical case series</td></tr><tr><td align="left" valign="top">Seo et al (2012) [<xref ref-type="bibr" rid="ref20">20</xref>]</td><td align="left" valign="top"><italic>Lasers in Surgery and Medicine</italic></td><td align="left" valign="top">Original research</td><td align="left" valign="top">Clinical and histologic study (prospective cohort)</td></tr><tr><td align="left" valign="top">Austin et al (2022) [<xref ref-type="bibr" rid="ref21">21</xref>]</td><td align="left" valign="top"><italic>Lasers in Surgery and Medicine</italic></td><td align="left" valign="top">Systematic review</td><td align="left" valign="top">Systematic review</td></tr></tbody></table></table-wrap></sec><sec id="s3-3"><title>RFMN-Related Tissue Changes</title><p>While RFMN effectively improves skin laxity and wrinkle reduction, its impact on future facelift procedures remains uncertain. An article published in 2022 found that a single session of noninvasive fractional bipolar RFMN achieved approximately 37% of the skin laxity improvement seen with a surgical facelift, suggesting multiple treatments may be required for significant results [<xref ref-type="bibr" rid="ref8">8</xref>]. However, a 2018 systematic review from the <italic>Journal of Plastic, Reconstructive &#x0026; Aesthetic Surgery</italic> states that repeated sessions risked dermal fibrosis, particularly in the papillary dermis, potentially complicating future surgical interventions [<xref ref-type="bibr" rid="ref9">9</xref>].</p><p>As RFMN devices introduce repeated and organized microtraumas into the skin, the depth of penetration directly impacts targeted tissue layers. Microneedling from such devices introduces a targeted mechanism of repair that excludes highly inflammatory cellular cascades, such as transforming growth factor &#x03B2;-1 (TGF-&#x03B2;1) and transforming growth factor &#x03B2;-2 (TGF-&#x03B2;2), and instead is driven through a less-inflammatory cascade via transforming growth factor &#x03B2;-3 (TGF-&#x03B2;3), a protein known to lead to fibroblast migration and collagen matrix remodeling [<xref ref-type="bibr" rid="ref10">10</xref>]. Platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), and epidermal growth factor (EGF) are all released locally in response to the microtrauma, allowing natural skin tightening via angiogenesis and collagen deposition [<xref ref-type="bibr" rid="ref2">2</xref>]. Repeated treatments thus increase collagen deposition, which increases the risk for the development of dermal fibrosis.</p><p>A better understanding of the timeline of collagenesis following RFMN is critical when considering the interplay with surgical facelifts. Acute inflammation and early collagen deposition dominate the first week after treatment, followed by organized collagen remodeling and maturation over the ensuing 1 to 3 months [<xref ref-type="bibr" rid="ref2">2</xref>,<xref ref-type="bibr" rid="ref10">10</xref>]. Persistent changes in dermal structure, including fibrosis or altered tensile strength, may interfere with surgical flap elevation, tissue pliability, and healing after a facelift.</p><p>RFMN energy settings can be optimized to balance skin tightening with control of fibrosis by titrating energy per needle, pulse duration, and depth to achieve sufficient dermal coagulation for neocollagenesis and elastogenesis while avoiding excessive thermal injury that may promote fibrotic remodeling. Data supports targeting moderate energy settings (eg, energy per needle 20&#x2010;60 mJ, pulse durations 100-300 ms) and limiting the number of passes to induce controlled dermal coagulation, maximizing skin tightening while minimizing the risk of fibrosis [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref12">12</xref>]. Adjusting needle depth to target the reticular dermis and using insulated needles can further localize RFMN thermal effects, thus reducing epidermal damage and unwanted fibrosis [<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref14">14</xref>]. Sequential or pulsed energy delivery, as well as energy feedback systems, can help regulate tissue response and prevent overtreatment [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref16">16</xref>].</p></sec><sec id="s3-4"><title>Effects on Future Elective Facelift Procedures</title><p>Surgical facelift procedures rely on the manipulation of the superficial musculoaponeurotic system (SMAS), a fibrofatty connective tissue layer continuous with the superficial cervical fascia, connected to the platysma muscle inferiorly and the galea superiorly [<xref ref-type="bibr" rid="ref17">17</xref>]. It plays an integral role in the anatomic relation of the superficial dermis to the underlying facial muscles. There are two distinct SMAS compositions given anatomic regions, and the abrupt junction of differing compositions resides at the nasolabial fold region, where medially, there are fewer fat lobules and a more direct connection of the SMAS to the superficial dermis as muscle fibers are seen to extend superficially into the dermis [<xref ref-type="bibr" rid="ref17">17</xref>]. However, the other regions of the SMAS lateral to the nasolabial fold still carry the same properties of communication of facial muscle to skin by muscle tendon fibers connecting both regions via the SMAS [<xref ref-type="bibr" rid="ref18">18</xref>]. Beneath this layer, the SMAS has a complex relation with deep ligaments and connections that limits the mobility of superficial structures. These connections are crucial to release to generate the most optimal movement for desired facelift outcomes [<xref ref-type="bibr" rid="ref17">17</xref>].</p><p>Due to the sophisticated relationship of neighboring structures, RFMN, particularly at greater depths, may alter these structural relationships. Traditional surgical facelifts target a single plane of tissue in a primary horizontal plane [<xref ref-type="bibr" rid="ref17">17</xref>]. On the contrary, RFMN targets a small treatment area in a vertical configuration through multiple planes of tissue, potentially leading to increased tissue adhesions, difficult surgical dissection, impaired flap mobility, and suboptimal facelift outcomes [<xref ref-type="bibr" rid="ref10">10</xref>].</p><p>Although undergoing RFMN treatments prior to a facelift could potentially induce a level of fibrosis that may help delay the timeline when a patient would be a candidate for a facelift, evidence suggests RFMN may be more beneficial postoperatively. Following a facelift, RFMN could enhance skin tightening and improve aesthetic outcomes by stimulating additional collagen production either as an immediate adjunctive therapy or as a method to combat recurrent long-term skin laxity [<xref ref-type="bibr" rid="ref19">19</xref>]. Careful planning is necessary to determine the appropriate time frame between treatments to avoid excessive fibrosis and impaired wound healing.</p></sec><sec id="s3-5"><title>Patient Considerations for RFMN Procedures</title><p>When considering therapy using RFMN, specific patient populations should be considered when discussing treatment options, as certain age groups, as well as patients with jowl laxity, have been shown to experience better outcomes with facial surgery [<xref ref-type="bibr" rid="ref19">19</xref>]. Taking into consideration that each treatment has varying mechanisms and different anatomical targets, a comparative study found that surgical facelifts improved skin laxity by 46% relative to baseline, whereas RFMN alone achieved only a 16% improvement [<xref ref-type="bibr" rid="ref20">20</xref>]. These findings underscore the importance of setting realistic patient expectations regarding treatment efficacy. Additionally, patient age should be considered, as older individuals (&#x2265;55 years) experience more pronounced skin tightening with RFMN compared to younger patients [<xref ref-type="bibr" rid="ref2">2</xref>]. Younger patients typically have a higher collagen content in their skin compared to older patients, who undergo collagen loss due to age; thus, the relative resulting decrease in skin laxity is much more noticeable in older patients versus younger patients. This knowledge prompts early discussion of RFMN treatment to address its potential effectiveness or lack thereof, especially at a younger age.</p><p>In addition to considering a patient&#x2019;s age, premature neck and jowl laxity are common concerns among patients seeking skin-tightening treatments. However, RFMN does not effectively target subplatysmal fat, necessitating careful patient selection&#x2014;individuals with significant subplatysmal fat may achieve superior results with surgical interventions such as liposuction [<xref ref-type="bibr" rid="ref19">19</xref>]. For patients with pronounced skin laxity, RFMN alone may be insufficient and could exacerbate sagging if incidental heat-induced fat loss occurs without concurrent skin excision [<xref ref-type="bibr" rid="ref19">19</xref>]. Other complications of RFMN reported include hyper- or hypopigmentation of treated skin, thermal burns, blistering, and scarring; these can often be mitigated with proper technique and equipment settings [<xref ref-type="bibr" rid="ref8">8</xref>].</p></sec></sec><sec id="s4" sec-type="discussion"><title>Discussion</title><sec id="s4-1"><title>Main Findings</title><p>The nuances of RFMN in facial rejuvenation necessitate a deeper understanding of its implications for future surgical facelifts. This calls for detailed discussion between the patient and health care provider to improve pretreatment consultation, patient education, and results. Patients should be informed that RFMN may lead to dermal fibrosis, tissue adhesions, subcutaneous adipose denaturation, and altered SMAS composition, which could complicate facelift procedures and their desired outcomes. Additionally, providers should address the limitations of RF to effectively target jowl laxity and set realistic expectations regarding RF results in patients younger than 55 years. Understanding these points would allow for individualized treatment planning, ensuring patients receive the most appropriate interventions based on their anatomical considerations and aesthetic goals. Furthermore, current evidence suggests RFMN may be better positioned as a postoperative adjunct rather than a presurgical intervention, especially in patients known to be surgical candidates in the future.</p><p>It is also important to note that RFMN has primarily been used for skin rejuvenation, mild laxity, and conditions such as acne scars, rather than as a substitute for surgical facelift procedures [<xref ref-type="bibr" rid="ref5">5</xref>]. Additional systematic reviews and clinical trials, such as those by Austin et al [<xref ref-type="bibr" rid="ref21">21</xref>] and Nguyen et al [<xref ref-type="bibr" rid="ref11">11</xref>], further support that early RFMN and radio frequency protocols are designed for modest rejuvenation, targeting mild-to-moderate laxity and stimulating collagen production. Among these studies, reported patient satisfaction was highest among those seeking subtle improvements rather than facelift-level results.</p></sec><sec id="s4-2"><title>Limitations</title><p>This scoping review is limited by the minimal availability of long-term studies specifically examining the effects of RFMN on subsequent surgical facelift procedures. The available literature mainly consists of case reports, small-scale studies, and expert opinion, which restricts the generalizability of conclusions. In addition, the large amount of variation between RFMN device settings, treatment protocols, and patient demographics across studies further limits the ability to standardize findings or establish definitive treatment guidelines.</p></sec><sec id="s4-3"><title>Conclusion</title><p>Cosmetic surgical providers trained in RFMN and/or facelift procedures should give careful consideration to this new technology when discussing different options for facial rejuvenation. Factors to weigh in these considerations should include, but are not limited to, age-related expectations, area of treatment, and the potential impact of subsequent facelifts. Rather than viewing RFMN and surgical facelifts as isolated interventions, providers should consider how early noninvasive treatments may influence future surgical options. This has important implications for clinical decision-making, patient education, and informed consent.</p><p>Ultimately, optimizing aesthetic outcomes will require a more integrated strategy that aligns patient goals with both immediate and long-term treatment trajectories. Future studies are needed to evaluate the cumulative impact of RFMN on facial anatomy and to guide safe, evidence-based treatment planning for patients considering both noninvasive and surgical facial rejuvenation options. Additional research should also focus on establishing guidelines for the optimal timing of RFMN relative to surgical facelifts and identifying strategies to minimize adverse effects of RFMN. As RFMN technology evolves, ongoing studies will be critical in refining its role in facial rejuvenation and improving patient outcomes.</p></sec></sec></body><back><ack><p>All authors declare no use of generative artificial intelligence in drafting any portion of the manuscript (this includes any and all tools, including ChatGPT, Gemini, Claude, or any other comparable tool not explicitly listed).</p></ack><notes><sec><title>Funding</title><p>The authors declare no financial support was received for this work.</p></sec></notes><fn-group><fn fn-type="conflict"><p>None declared.</p></fn></fn-group><glossary><title>Abbreviations</title><def-list><def-item><term id="abb1">EGF</term><def><p>epidermal growth factor</p></def></def-item><def-item><term id="abb2">FGF</term><def><p>fibroblast growth factor</p></def></def-item><def-item><term id="abb3">PDGF</term><def><p>platelet-derived growth factor</p></def></def-item><def-item><term id="abb4">PRISMA-ScR</term><def><p>Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews</p></def></def-item><def-item><term id="abb5">RF</term><def><p>radio frequency</p></def></def-item><def-item><term id="abb6">RFMN</term><def><p>radio frequency microneedling</p></def></def-item><def-item><term id="abb7">SMAS</term><def><p>superficial musculoaponeurotic system</p></def></def-item><def-item><term id="abb8">TGF-&#x03B2;1</term><def><p>transforming growth factor &#x03B2;-1</p></def></def-item><def-item><term id="abb9">TGF-&#x03B2;2</term><def><p>transforming growth factor &#x03B2;-2</p></def></def-item><def-item><term id="abb10">TGF-&#x03B2;3</term><def><p>transforming growth factor &#x03B2;-3</p></def></def-item></def-list></glossary><ref-list><title>References</title><ref id="ref1"><label>1</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Devgan</surname><given-names>L</given-names> </name><name 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