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Currently submitted to: JMIR Dermatology

Date Submitted: Jul 27, 2020
Open Peer Review Period: Jul 27, 2020 - Sep 21, 2020
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A Unique Case of Cutaneous Cunninghamella infection in an Immunocompromised Patient

  • Mauricio Portillo; 
  • Shyam Allamaneni; 
  • Richard Goodman; 


Cunninghamella species are an extremely rare cause of fungal infections. The usual mode of transmission is through inhalation however rare cases of cutaneous spread have been reported. The objective of this clinical case report is to highlight the uniqueness of which the patient acquired the infection, the progression, and control of it. A 57-year-old male with chronic lymphocytic leukemia was found to have an abscess next to his peripherally inserted central catheter (PICC) line. The abscess culture grew back Cunninghamella and was debrided and treated with a novel antifungal. The fungal infection was controlled and the total timeframe took 28 days. Rapid recognition and prompt treatment demonstrate the prevention of rapidly progressive angioinvasian and further systemic complications. This case also proves that a novel antifungal may be appropriate in controlling the spread of Cunninghamella species.


Please cite as:

Portillo M, Allamaneni S, Goodman R

A Unique Case of Cutaneous Cunninghamella infection in an Immunocompromised Patient

JMIR Preprints. 27/07/2020:22935

DOI: 10.2196/preprints.22935


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