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Examining Weight Suppression, Leptin Levels, Glucagon-Like Peptide 1 Response, and Reward-Related Constructs in Severity and Maintenance of Bulimic Syndromes: Protocol and Sample Characteristics for a Cross-Sectional and Longitudinal Study

Examining Weight Suppression, Leptin Levels, Glucagon-Like Peptide 1 Response, and Reward-Related Constructs in Severity and Maintenance of Bulimic Syndromes: Protocol and Sample Characteristics for a Cross-Sectional and Longitudinal Study

We observed stability in BMI across days (r>0.95; P The Eating Disorder Examination (EDE) 17.0 D [83] was selected due to previous evidence of good discriminant validity [84-87], IRR (0.83 to 0.99) [88,89], and good internal consistency of the restraint and body image subscales (Cronbach α>0.70) [90].

Pamela K Keel, Lindsay P Bodell, Sarrah I Ali, Austin Starkey, Jenna Trotta, J Woody Luxama, Chloé Halfhide, Naomi G Hill, Jonathan Appelbaum, Diana L Williams

JMIR Res Protoc 2025;14:e66554

Digital Health Intervention to Reduce Malnutrition Among Individuals With Gastrointestinal Cancer Receiving Cytoreductive Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy: Feasibility, Acceptability, and Usability Trial

Digital Health Intervention to Reduce Malnutrition Among Individuals With Gastrointestinal Cancer Receiving Cytoreductive Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy: Feasibility, Acceptability, and Usability Trial

Compared to baseline, average PG-SGA malnutrition scores saw a decrease of 6 points (P=.01), with a corresponding reduction in patients with high malnutrition risk (P=.03; Table 4). Functional Assessment of Cancer Therapy—General scores increased by an average of 20.5 points (P=.002), and Functional Assessment of Anorexia/Cachexia Treatment—Anorexia/Cachexia Scale scores increased by an average of 7.4 points (P=.03), indicating an improvement in participants’ health-related quality of life.

Yu Chen Lin, Ryan Hagen, Benjamin D Powers, Sean P Dineen, Jeanine Milano, Emma Hume, Olivia Sprow, Sophia Diaz-Carraway, Jennifer B Permuth, Jeremiah Deneve, Amir Alishahi Tabriz, Kea Turner

JMIR Cancer 2025;11:e67108

Innovating Care for Postmenopausal Women Using a Digital Approach for Pelvic Floor Dysfunctions: Prospective Longitudinal Cohort Study

Innovating Care for Postmenopausal Women Using a Digital Approach for Pelvic Floor Dysfunctions: Prospective Longitudinal Cohort Study

Statistical significance was defined as P Of the 3684 participants screened for eligibility, 633 participants were excluded (346 declined participation and 287 did not meet eligibility criteria; Figure 2). The program started with 3051 participants, of which 2367 participants completed it, translating into a completion rate of 77.6%. Study flowchart.

Ana P Pereira, Dora Janela, Anabela C Areias, Maria Molinos, Xin Tong, Virgílio Bento, Vijay Yanamadala, Jennesa Atherton, Fernando Dias Correia, Fabíola Costa

JMIR Mhealth Uhealth 2025;13:e68242

Impact of a 6-Week Postpartum Text Messaging Program (Essential Coaching for Every Mother) at 6 Months: Follow-Up Study to a Randomized Controlled Trial

Impact of a 6-Week Postpartum Text Messaging Program (Essential Coaching for Every Mother) at 6 Months: Follow-Up Study to a Randomized Controlled Trial

This differed from baseline, as there was no difference in race but mothers in the control group were significantly older than mothers in the intervention group (P=.053) [11]. At baseline, there were no differences between the groups on any of the primary outcomes [11]. Additional demographic details are available in Table 1 and Dol et al [11]. Consolidated Standards of Reporting Trails (CONSORT) flowchart.

Justine Dol, Marsha Campbell-Yeo, Megan Aston, Douglas McMillan, Amy K Grant

JMIR Pediatr Parent 2025;8:e62841

Impact of a Symptom Checker App on Patient-Physician Interaction Among Self-Referred Walk-In Patients in the Emergency Department: Multicenter, Parallel-Group, Randomized, Controlled Trial

Impact of a Symptom Checker App on Patient-Physician Interaction Among Self-Referred Walk-In Patients in the Emergency Department: Multicenter, Parallel-Group, Randomized, Controlled Trial

We report group means and SDs, the linear mixed model estimator, 95% CIs, and P values. Statistical analyses were conducted using R (version 4.4.0; R Foundation) [67], with data cleaning performed using tidyverse [68]. CIs were bootstrapped, and P values were calculated using the R packages lme4 [69] and parameters [70].

Malte L Schmieding, Marvin Kopka, Myrto Bolanaki, Hendrik Napierala, Maria B Altendorf, Doreen Kuschick, Sophie K Piper, Lennart Scatturin, Konrad Schmidt, Claudia Schorr, Alica Thissen, Cornelia Wäscher, Christoph Heintze, Martin Möckel, Felix Balzer, Anna Slagman

J Med Internet Res 2025;27:e64028