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Skip search results from other journals and go to results- 3 JMIR Dermatology
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Lichen Planus Pigmentosus and Vitiligo in a 61-Year-Old Filipino Man: Case Report
Vitiligo is a rare, chronic disorder that appears in about 1% of the population, causing depigmentation of the skin without preceding inflammation [3]. Although clinically opposite in presentation, autoimmunity has been implicated in these 2 conditions [4].
Pigmentary disorders are a source of psychosocial turmoil and cosmetic disfigurement. The quality of life of patients with LPP and vitiligo was found to be more significantly affected than that of patients with melasma [5].
JMIR Dermatol 2024;7:e50401
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According to a meta-analysis study, the prevalence of depression among patients with vitiligo is 25.3% [5].
Patients with vitiligo often exhibit a dysregulated immune system, which may be exacerbated by concomitant depression. Clinical and animal studies suggest that depression can aggravate vitiligo, as both conditions share similar leukocyte signatures and inflammatory genetic mechanisms associated with systemic autoimmune inflammation.
JMIR Dermatol 2024;7:e60686
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Vitiligo and Metabolic Syndrome: Systematic Review and Meta-Analysis
In fact, several articles have reported a strong association between vitiligo and both type 1 and 2 diabetes mellitus; while the association between vitiligo and type 1 diabetes is not surprising given the autoimmune nature of both conditions, the association with type 2 diabetes necessitates close surveillance for metabolic derangements [17,18]. Despite the relationship between vitiligo and type 2 diabetes mellitus, few studies have investigated the relationship between vitiligo and Met S.
JMIR Dermatol 2022;5(1):e34772
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