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Lichen Planus Pigmentosus and Vitiligo in a 61-Year-Old Filipino Man: Case Report

Lichen Planus Pigmentosus and Vitiligo in a 61-Year-Old Filipino Man: Case Report

The patient significantly improved following 4 months of low-dose oral isotretinoin for LPP and tacrolimus 0.1% ointment for both LPP and vitiligo. This case report was obtained in private practice and is published for educational purposes rather than for research. Informed consent was obtained. Since there was no intervention given to the patient that deviated from standard practice, no institutional review board approval was required.

Maria Isabel Belizario, Julius Garcia Gatmaitan, Johannes Dayrit

JMIR Dermatol 2024;7:e50401

From the Cochrane Library: Topical Tacrolimus for Atopic Dermatitis

From the Cochrane Library: Topical Tacrolimus for Atopic Dermatitis

A 2015 Cochrane review, titled “Topical tacrolimus for atopic dermatitis,” assessed the efficacy and safety of the topical calcineurin inhibitors (TCIs) tacrolimus and pimecrolimus in comparison to conventional treatments (20 randomized controlled trials, n=5885) [2]. Significant drug comparison findings are summarized in Table 1.

Austin Hamp, Jarett D Anderson, Torunn E Sivesind, Mindy D Szeto, Jade Cury-Martins

JMIR Dermatol 2021;4(2):e31838

Impact of Electronic Health Record Interface Design on Unsafe Prescribing of Ciclosporin, Tacrolimus, and Diltiazem: Cohort Study in English National Health Service Primary Care

Impact of Electronic Health Record Interface Design on Unsafe Prescribing of Ciclosporin, Tacrolimus, and Diltiazem: Cohort Study in English National Health Service Primary Care

Tacrolimus and ciclosporin are used in organ transplantation and other conditions, such as rheumatoid arthritis, psoriasis, and severe atopic dermatitis. Both medicines have a narrow therapeutic window: minor differences in blood levels have the potential to cause graft rejection reactions, and switching between tacrolimus products has been associated with reports of toxicity and graft rejection.

Brian John MacKenna, Sebastian Bacon, Alex J Walker, Helen J Curtis, Richard Croker, Ben Goldacre

J Med Internet Res 2020;22(10):e17003