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Skip search results from other journals and go to results- 3 JMIR Research Protocols
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Nutrition, Obesity, and Seborrheic Dermatitis: Systematic Review
They found that vitamin D deficiency was more prevalent in patients with seborrheic dermatitis than in controls (P=.01). This team neither obtained follow-up serum levels of vitamin D nor determined if subsequent supplementation resulted in seborrheic dermatitis improvement, thus it is difficult to conclude if supplementation is clinically beneficial.
JMIR Dermatol 2024;7:e50143
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On the other hand, there has recently been renewed interest in the use of high-dose vitamin C as a supportive treatment in patients with severe septic shock (metabolic resuscitation) [27]. Sepsis has been shown to decrease the levels of some vitamins, such as ascorbic acid, which has been associated with the development of multiorgan failure and death. Intestinal absorption of vitamin C is saturable, so the only way to increase its levels would be by intravenous administration.
JMIR Res Protoc 2023;12:e50091
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Clinical Efficacy of Nutritional Supplements in Atopic Dermatitis: Systematic Review
Patients receiving vitamin E showed a significant reduction in SCORAD scores compared with baseline (35.7%; P
This study also evaluated the effects of a combined regimen of 600 IU of vitamin E and 1600 IU of vitamin D3 daily for 60 days [7]. This group showed a significant and marked improvement in SCORAD scores (64.3%; P
Overall, there is minimal evidence supporting the efficacy of vitamin D or E for the treatment of AD.
JMIR Dermatol 2023;6:e40857
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Single, double, and multiple vitamin supplementation (including micronutrient powders, tablets, syrups, and lipid-based micronutrient supplements)
Author-defined (placebo, only iron supplement, only iron and folic acid supplement, or no care)
Micronutrient deficiencies
Vitamin A serum/plasma/breastmilk retinol
Vitamin B1 serum/plasma thiamine
Vitamin B2 serum/plasma riboflavin (flavoenzymes flavin mononucleotide and flavin adenine dinucleotide)
Vitamin B3 serum/plasma (niacin and metabolite)
Vitamin B5 serum
JMIR Res Protoc 2022;11(8):e40134
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Ascorbic acid deficiency, or vitamin C deficiency, has been reported in patients with severe infection [12,13], with preclinical data lending credence to the use of vitamin C in sepsis. Supplementation with vitamin C has been postulated to reduce vascular endothelial injury in pulmonary and systemic vasculature and reduce oxidative damage, and vitamin C has been postulated to act synergistically with glucocorticoids to suppress inflammation [14].
JMIR Res Protoc 2022;11(1):e33989
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Therefore, in order to analyze the public’s actual interest in immune system strength, we selected the term vitamin as a keyword. For the United States and the United Kingdom, the term vitamin was used. For Italy, the term vitamina was used. Finally, for South Korea, the Korean-language spelling of the term vitamin was used.
J Med Internet Res 2021;23(6):e26368
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