Published on in Vol 7 (2024)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/60282, first published .
US Public Interest in Merkel Cell Carcinoma Following Jimmy Buffett’s Death and Implications for Continued Health Advocacy: Infodemiology Study of Google Trends

US Public Interest in Merkel Cell Carcinoma Following Jimmy Buffett’s Death and Implications for Continued Health Advocacy: Infodemiology Study of Google Trends

US Public Interest in Merkel Cell Carcinoma Following Jimmy Buffett’s Death and Implications for Continued Health Advocacy: Infodemiology Study of Google Trends

1Office of Medical Student Research, Oklahoma State University College of Osteopathic Medicine at the Cherokee Nation, , 19500 E Ross St, Tahlequah, OK, , United States

2Department of Emergency Medicine, Oklahoma State University Center for Health Sciences, , Tulsa, OK, , United States

3Department of Psychiatry and Behavioral Sciences, Oklahoma State University Center for Health Sciences, , Tulsa, OK, , United States

*all authors contributed equally

Corresponding Author:

Macy Haight, BSc


Through Jimmy Buffett’s unfortunate battle with lymphoma originating from Merkel cell carcinoma and subsequent media coverage of his death, public interest in skin cancer, Merkel cell carcinoma, and the health effects of sunlight exposure increased, as evidenced by our results.

JMIR Dermatol 2024;7:e60282

doi:10.2196/60282

Keywords



Analyzing public interest in health-related topics through web-based search inquiries has become increasingly popular within the health care community over the past decade [1]. Infodemiology—the study of the “distribution and determinants of information across electronic platforms”—provides valuable insights into health information–seeking behavior [2]. Infodemiology research often relies on data from sources such as Google Trends, which aggregates and anonymizes search data from Google’s search engine. Unlike traditional data collection methods, Google Trends offers real-time data that can be stratified by geographical region and time period. Google Trends’ utility in quantifying public interest in health topics and identifying health information–seeking behavior trends has been studied, proving to be an effective means of evaluating public interest in health-related topics [3].

With the rise of social media and celebrities’ transparency regarding personal health issues, infodemiology provides a means of quantifying public interest in health information across electronic platforms [4]. Celebrity health events have been shown to significantly impact public interest in specific diseases and health behaviors. The “Angelina Jolie effect,” for example, led to a surge in referrals to breast cancer clinics and genetics services following the actress’ decision to undergo a preventive double mastectomy. Similarly, media coverage of celebrity cancer diagnoses and deaths has been linked to increased public interest in cancer-related topics [5,6].

Singer-songwriter Jimmy Buffett, who famously sang “Some of it’s magic, some of it’s tragic, but I had a good life all the way,” tragically died on September 1, 2023, after battling lymphoma precipitating from Merkel cell carcinoma (MCC) [7,8]. Buffett’s death received widespread media coverage, prompting renewed interest in this rare disease among the general public [9]. To investigate the impact of celebrity health events on public interest regarding specific health-related topics, we conducted an analysis of search interest surrounding this rare and aggressive skin cancer, using Google Trends.


Study Design

Google Trends was used to quantify search interest in “skin cancer,” “Merkel cell carcinoma,” and “health effects of sunlight exposure” in all US regions for a 60-day period encompassing Buffett’s death. Daily relative search interest (RSI) data were extracted from Google Trends from August 2 through September 30, 2023. RSI is a value from 0 to 100 based on the highest volume criteria within the search. An autoregressive integrated moving algorithm was trained on data from August 2 through September 2, 2023, to forecast daily search volume and 95% CIs for September 3 through September 30, 2023, as if the event did not occur. We then compared forecasted values to the actual values to note peak changes during the time frame and where the actual RSI falls outside the forecasted 95% CI to identify statistically significant values (P<.05).

Ethical Considerations

This study did not involve human subjects, as defined under US Department of Health and Human Services regulations 45 CFR Part 46. Therefore, institutional review board approval was not required. We used publicly available, deidentified data from Google Trends, which aggregates search behavior from large populations and ensures that all information is anonymized, with no personal identifiers or sensitive data associated with individual users.


Our analysis revealed statistically significant increases in search interest for MCC and related topics following Buffett’s death (Figure 1 and Table 1). Peak search interest occurred 3 days after Buffett’s death (RSI=100), with sustained interest observed up to 15 days after the event. Percent differences between the actual and projected RSI values for the search terms during this 15-day period ranged from 95.79% to 21,968.97%, indicating the substantial impact of Buffett’s death on public awareness of MCC.

Figure 1. Relative search interest for “skin cancer,” “Merkel cell carcinoma,” and “health effects of sunlight exposure” in the United States by date.
Table 1. Relative search interest (RSI) percent difference by search term, with 95% CIs for a 60-day period encompassing Buffett’s death.
Forecasted RSI (95% CI)Actual RSI% difference
“Skin Cancer”8.63 (4.33‐12.92)1001059.42
“Merkel Cell Carcinoma”0.45 (0.17‐0.74)10021,968.97
“Health Effects of Sunlight Exposure”51.07 (23.04‐79.11)10095.79

Our analysis of temporal search interest trends provides insights into the immediate impact of a celebrity’s health event on public engagement with skin cancer information. The sustained interest in MCC following Buffett’s death highlights the potential crucial role of infodemiology research in understanding impacts of celebrity health events on public health behaviors. By leveraging tools such as Google Trends, researchers can gain valuable insights into health information–seeking behavior patterns and identify opportunities for targeted public health interventions.

Although celebrity endorsements and media coverage can raise short-term awareness, sustained efforts are needed to ensure that awareness translates into meaningful action. By monitoring health information–seeking behavior trends, researchers can identify areas where targeted interventions and strategies are needed to promote long-term behavioral change. As we navigate the complex interplay between media influence and public health, our study contributes to ongoing discussions on optimizing strategies for increasing awareness and improving health outcomes associated with diseases, such as MCC.

Acknowledgments

MH receives research funding from the National Institute of Child Health and Human Development (U54HD113173; Karina Shreffler), from the Human Resources Services Administration (U4AMC44250-01-02, principal investigator [PI]: Audra Haney; R41MC45951, PI: MH), and previously from the National Institute of Justice (2020-R2-CX-0014, PI: Jason Beaman)—all unrelated to this paper.

Conflicts of Interest

None declared.

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MCC: Merkel cell carcinoma
RSI: relative search interest


Edited by Robert Dellavalle; submitted 06.05.24; peer-reviewed by John Meisenheimer, Mary Buller; final revised version received 05.09.24; accepted 28.09.24; published 31.10.24.

Copyright

© Macy Haight, Hayden R Jacobs, Sarah K Boltey, Kelly A Murray, Micah Hartwell. Originally published in JMIR Dermatology (http://derma.jmir.org), 31.10.2024.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Dermatology, is properly cited. The complete bibliographic information, a link to the original publication on http://derma.jmir.org, as well as this copyright and license information must be included.