JMIR Dermatology
JMIR Dermatology is the official journal of the International Society of Digital Health in Dermatology (ISDHD), formerly the International Society of Teledermatology (ISTD).
Editor-in-Chief:
Robert Dellavalle, MD, PhD, MSPH, Professor and Head, Department of Dermatology, University of Minnesota Medical School
CiteScore 1.8
Recent Articles

Dermatology is an ever-evolving field; the integration of artificial intelligence (AI) offers promising avenues for enhancing clinical decision-making and improving patient outcomes. This study focuses on evaluating the effectiveness of DermGPT, an AI model specifically designed to address dermatological inquiries with precision, compared to ChatGPT-4o (OpenAI), an AI chatbot and virtual assistant developed by OpenAI. DermGPT was developed by a practicing dermatologist, and it is marketed as a superior alternative to general-purpose AI models like ChatGPT; it contains a curated database of authoritative sources tailored to the community of dermatological professionals.

This single-center retrospective case series included 28 patients with alopecia (LPP, n =7; DLE, n =7; AA, =14). Trichoscopic markers were systematically compared across groups. Exclamation-mark hairs and yellow dots were characteristic of AA, whereas follicular ostia loss and white scarring were confined to LPP/DLE, providing a simple and practical distinction between nonscarring and scarring alopecias in routine practice.

Chronic spontaneous urticaria (CSU) is an autoimmune prompted skin disorder whose hallmarks include the unpredictable onset of hives and itch [1,2]. Symptom duration typically exceed 6 weeks, and flares can occur for up to 5 years or longer if untreated [3], impacting potentially any area of the body [4]. The absence of obvious triggers and the variation in onset frequency often delays formal diagnosis which on average is ~ 2 years from first presentation [5]. Initial standard of care is the use of low through to higher strength antihistamines in first instance, with eventual escalation to prescription anti-inflammatory agents and potentially biologics once patients are under managed care [6]. The societal impacts of delays in diagnosis are marked, with data suggesting CSU impacts up to 1% of the population, primarily of working age and with twice the prevalence in women [5]. Herein we advocate for the deployment of smartphone imaging and generative AI technology to improve detection and early management of CSU through integrated self-care approaches. Such approaches, embodying the tenets of P4 personalized medicine [7], could have sustained impact on the disease through awareness campaigns, reducing the burden on the dermatology community and facilitating earlier access to curative therapeutic interventions.

Acral Persistent Papular Mucinosis (APPM) is a localized variant of lichen myxedematosus (LM) characterized by asymptomatic, flesh-colored papules primarily distributed on the hands and forearms. This chronic dermatosis, distinct from generalized mucinosis due to its lack of systemic involvement, remains underreported in medical literature.

Medical students' comparison of dermatological cases generated by AI versus those created without AI revealed that AI-created cases were characterized by detailed case descriptions, analysis of medical history, clinical examinations, but lacked the depth, clinical relevance, and motivational elements found in non-AI cases, which were shorter, presented clinical dilemmas and included challenging scenarios that students found more educational and engaging.


Dermal fillers have gained increasing popularity for their ability to enhance facial symmetry, restore volume, and improve skin texture. However, their use in cancer patients undergoing active chemotherapy and radiation therapy poses unique challenges, as these treatments can alter both the safety profile and efficacy of filler procedures. Chemotherapy can interfere with normal wound healing and immune responses, warranting a more cautious and individualized approach when considering dermal fillers in this population. Although rare, dermal fillers have been associated with adverse outcomes in a limited number of reports, including cellulitis, ASIA, and a possible predisposition to malignancy. Other effects include localized inflammatory, systemic hypersensitivity, and delayed granulomatous formation, and these could be more severe in patients undergoing antineoplastic therapy. Furthermore, chemotherapy is often paired with adjuvant radiation therapy in cancer treatment, making it important to note the potential changes radiation can have on the skin. More research is needed to examine the direct interactions of chemotherapy and radiation on various filler materials injected within the skin, and how these can alter one's risk of adverse effects. The lack of research on this topic further emphasizes that clinicians should thoroughly educate patients receiving chemotherapy and adjuvant radiation treatment about the heightened potential risks associated with dermal filler injections and treatment regimens should be planned accordingly to minimize any adverse events.
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